Distribution of CD68 and CD3 immune cells in the cervix of women with infectious and non-infectious immunodeficiency

Women with immunodeficiency conditions are a separate cohort of patients who need the close attention doctors and social workers. The aim study was to determine distribution CD68 CD3 immune cells in cervix women infectious non-infectious immunodeficiency, namely, HIV infection, chronic alcoholism their combination. Research groups were formed based on results autopsies 100 reproductive age, 25 cases each group: group alcoholism, combination infection comparison group. An immunohistochemical performed monoclonal antibodies CD3. During research it established that is characterized by decrease epithelial layer both HIV-infected (up (1.06±0.13) cells/mm2 for without up (1.09±0.11) alcoholism), while abuse alcohol, this indicator increased (1.96±0.15) (p<0.05). In stroma, accumulation CD68-positive tends all groups. dynamics CD3-positive different zones epithelium groups, alcohol number (p<0.05) (3.86±0.14) cells/mm2. Simultaneously, stroma infiltration three significant increase (8.13±0.79), (9.89±0.57) (9.04±0.75) respectively Based study, can be concluded variability depending nature immunodeficiency. Keywords: cervical mucosa, response, HIV-infection, lymphocytes.